Equity

IBB

iShares Biotechnology ETF

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Overview

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iSHARES MARKET INSIGHT

2024 Thematic Outlook

Learn about three themes that we believe will be key to navigating the year ahead.

Key Facts

Key Facts

Net Assets of Fund as of Mar 27, 2024 $7,674,222,005
Fund Inception Feb 05, 2001
Exchange NASDAQ
Asset Class Equity
Benchmark Index NYSE Biotechnology Index
Bloomberg Index Ticker ICEBIOT
Shares Outstanding as of Mar 27, 2024 55,700,000
Distribution Frequency Quarterly
Premium/Discount as of Mar 27, 2024 0.01
CUSIP 464287556
Closing Price as of Mar 27, 2024 137.79
30 Day Avg. Volume as of Mar 27, 2024 1,927,716.00
30 Day Median Bid/Ask Spread as of Mar 27, 2024 0.01%
Daily Volume as of Mar 27, 2024 1,274,010.00

Portfolio Characteristics

Portfolio Characteristics

Number of Holdings as of Mar 27, 2024 219
Equity Beta (3y) as of Feb 29, 2024 0.74
30 Day SEC Yield as of Feb 29, 2024 0.17%
12m Trailing Yield as of Feb 29, 2024 0.25%
Standard Deviation (3y) as of Feb 29, 2024 18.74%
P/E Ratio as of Mar 27, 2024 25.88
P/B Ratio as of Mar 27, 2024 4.20
Unsubsidized 30-Day SEC Yield as of Feb 29, 2024 0.17%
This information must be preceded or accompanied by a current prospectus. For standardized performance, please see the Performance section above.

Sustainability Characteristics

Sustainability Characteristics

Sustainability Characteristics provide investors with specific non-traditional metrics. Alongside other metrics and information, these enable investors to evaluate funds on certain environmental, social and governance characteristics. Sustainability Characteristics do not provide an indication of current or future performance nor do they represent the potential risk and reward profile of a fund. They are provided for transparency and for information purposes only. Sustainability Characteristics should not be considered solely or in isolation, but instead are one type of information that investors may wish to consider when assessing a fund. Learn more


This fund does not seek to follow a sustainable, impact or ESG investment strategy. The metrics do not change the fund’s investment objective or constrain the fund’s investable universe, and there is no indication that a sustainable, impact or ESG investment strategy will be adopted by the fund. For more information regarding the fund's investment strategy, please see the fund's prospectus.


Review the MSCI methodologies behind Sustainability Characteristics using the links below.

MSCI ESG Fund Rating (AAA-CCC) as of Mar 21, 2024 A
MSCI ESG % Coverage as of Mar 21, 2024 85.79%
MSCI ESG Quality Score (0-10) as of Mar 21, 2024 6.4
MSCI ESG Quality Score - Peer Percentile as of Mar 21, 2024 44.19%
Fund Lipper Global Classification as of Mar 21, 2024 Equity Sector Healthcare
Funds in Peer Group as of Mar 21, 2024 525
MSCI Weighted Average Carbon Intensity (Tons CO2E/$M SALES) as of Mar 21, 2024 21.20
MSCI Weighted Average Carbon Intensity % Coverage as of Mar 21, 2024 85.95%
MSCI Implied Temperature Rise (0-3.0+ °C) as of Mar 21, 2024 > 1.5° - 2.0° C
MSCI Implied Temperature Rise % Coverage as of Mar 21, 2024 81.35%

What is the Implied Temperature Rise (ITR) metric? Learn what the metric means, how it is calculated, and about the assumptions and limitations for this forward-looking climate-related metric.

To address climate change, many of the world's major countries have signed the Paris Agreement. The temperature goal of the Paris Agreement is to limit global warming to well below 2°C above pre-industrial levels, and ideally 1.5 °C, which will help us avoid the most severe impacts of climate change.


What is the ITR metric?

The ITR metric is used to provide an indication of alignment to the temperature goal of the Paris Agreement for a company or a portfolio. ITR employs open source 1.55° C decarbonization pathways derived from the Network of Central Banks and Supervisors for Greening the Financial System (NGFS). These pathways can be regional and sector specific and set a net zero target of 2050, in line with GFANZ (Glasgow Financial Alliance for Net Zero) industry standards. We make use of this feature for all GHG scopes. This enhanced ITR model was implemented by MSCI on February 19, 2024.


How is the ITR metric calculated?

The ITR metric is calculated by looking at the current emissions intensity of companies within the fund's portfolio as well as the potential for those companies to reduce its emissions over time. If emissions in the global economy followed the same trend as the emissions of companies within the fund's portfolio, global temperatures would ultimately rise within this band.


Note, only corporate issuers are covered within the calculation. A summary explanation of MSCI’s methodology and assumptions for its ITR metric can be found here.


Because the ITR metric is calculated in part by considering the potential for a company within the fund’s portfolio to reduce its emissions over time, it is forward-looking and prone to limitations. As a result, BlackRock publishes MSCI’s ITR metric for its funds in temperature range bands. The bands help to underscore the underlying uncertainty in the calculations and the variability of the metric.

Thermometer-style chart of yellow to red temperature bands showing an investment’s position relative to the Paris Agreement temperature goals. Metric data source MSCI

What are the key assumptions and limitations of the ITR metric?

This forward-looking metric is calculated based on a model, which is dependent upon multiple assumptions. Also, there are limitations with the data inputs to the model. Importantly, an ITR metric may vary meaningfully across data providers for a variety of reasons due to methodological choices (e.g., differences in time horizons, the scope(s) of emissions included and portfolio aggregation calculations).

There is not a universally accepted way to calculate an ITR. There is not a universally agreed upon set of inputs for the calculation. At present, availability of input data varies across asset classes and markets. To the extent that data becomes more readily available and more accurate over time, we expect that ITR metric methodologies will evolve and may result in different outputs. Funds may change bands as methodologies evolve. Where data is not available, and / or if data changes, the estimation methods vary, particularly those related to a company’s future emissions.


The ITR metric estimates a fund’s alignment with the Paris Agreement temperature goal based on a credibility assessment of stated decarbonization targets. However, there is no guarantee that these estimates will be reached. The ITR metric is not a real time estimate and may change over time, therefore it is prone to variance and may not always reflect a current estimate.


The ITR metric is not an indication or estimate of a fund’s performance or risk. Investors should not rely on this metric when making an investment decision and instead should refer to a fund’s prospectus and governing documents. This estimate and the associated information is not intended as a recommendation to invest in any fund, nor is it intended to indicate any correlation between a fund’s ITR metric and its future investment performance.

All data is from MSCI ESG Fund Ratings as of Mar 21, 2024, based on holdings as of Feb 29, 2024. As such, the fund’s sustainable characteristics may differ from MSCI ESG Fund Ratings from time to time.

To be included in MSCI ESG Fund Ratings, 65% (or 50% for bond funds and money market funds) of the fund’s gross weight must come from securities with ESG coverage by MSCI ESG Research (certain cash positions and other asset types deemed not relevant for ESG analysis by MSCI are removed prior to calculating a fund’s gross weight; the absolute values of short positions are included but treated as uncovered), the fund’s holdings date must be less than one year old, and the fund must have at least ten securities.

Business Involvement

Business Involvement

Business Involvement metrics can help investors gain a more comprehensive view of specific activities in which a fund may be exposed through its investments.


Business Involvement metrics are not indicative of a fund’s investment objective, and, unless otherwise stated in fund documentation and included within a fund’s investment objective, do not change a fund’s investment objective or constrain the fund’s investable universe. For more information regarding a fund's investment strategy, please see the fund's prospectus.


Review the MSCI methodology behind the Business Involvement metrics, using links below.

MSCI - Controversial Weapons as of Mar 27, 2024 0.00%
MSCI - UN Global Compact Violators as of Mar 27, 2024 0.00%
MSCI - Nuclear Weapons as of Mar 27, 2024 0.00%
MSCI - Thermal Coal as of Mar 27, 2024 0.00%
MSCI - Civilian Firearms as of Mar 27, 2024 0.00%
MSCI - Oil Sands as of Mar 27, 2024 0.00%
MSCI - Tobacco as of Mar 27, 2024 0.00%

Business Involvement Coverage as of Mar 27, 2024 99.67%
Percentage of Fund not covered as of Mar 27, 2024 0.33%
BlackRock business involvement exposures as shown above for Thermal Coal and Oil Sands are calculated and reported for companies that generate more than 5% of revenue from thermal coal or oil sands as defined by MSCI ESG Research. For the exposure to companies that generate any revenue from thermal coal or oil sands (at a 0% revenue threshold), as defined by MSCI ESG Research, it is as follows: Thermal Coal 0.00% and for Oil Sands 0.00%.

Business Involvement metrics are calculated by BlackRock using data from MSCI ESG Research which provides a profile of each company’s specific business involvement. BlackRock leverages this data to provide a summed up view across holdings and translates it to a fund's market value exposure to the listed Business Involvement areas above.


Business Involvement metrics are designed only to identify companies where MSCI has conducted research and identified as having involvement in the covered activity. As a result, it is possible there is additional involvement in these covered activities where MSCI does not have coverage. This information should not be used to produce comprehensive lists of companies without involvement. Business Involvement metrics are only displayed if at least 1% of the fund’s gross weight includes securities covered by MSCI ESG Research.

Fees

Fees

as of current prospectus
Management Fee 0.45%
Acquired Fund Fees and Expenses 0.00%
Other Expenses 0.00%
Expense Ratio 0.45%

The amounts shown above are as of the current prospectus, but may not include extraordinary expenses incurred by the Fund over the past fiscal year. Amounts are rounded to the nearest basis point, which in some cases may be "0.00".

Ratings

iShares Biotechnology ETF Fund Holdings as of,"Mar 27, 2024" Inception Date,"Feb 05, 2001" Shares Outstanding,"55,700,000.00" Stock,"-" Bond,"-" Cash,"-" Other,"-"   Ticker,Name,Sector,Asset Class,Market Value,Weight (%),Notional Value,Shares,Price,Location,Exchange,Currency,FX Rate,Market Currency,Accrual Date "AMGN","AMGEN INC","Health Care","Equity","645,756,521.20","8.43","645,756,521.20","2,255,524.00","286.30","United States","NASDAQ","USD","1.00","USD","-" "GILD","GILEAD SCIENCES INC","Health Care","Equity","625,425,563.00","8.16","625,425,563.00","8,566,300.00","73.01","United States","NASDAQ","USD","1.00","USD","-" "REGN","REGENERON PHARMACEUTICALS INC","Health Care","Equity","617,763,320.40","8.06","617,763,320.40","639,308.00","966.30","United States","NASDAQ","USD","1.00","USD","-" "VRTX","VERTEX PHARMACEUTICALS INC","Health Care","Equity","612,610,319.16","8.00","612,610,319.16","1,467,963.00","417.32","United States","NASDAQ","USD","1.00","USD","-" "IQV","IQVIA HOLDINGS INC","Health Care","Equity","340,954,345.80","4.45","340,954,345.80","1,349,940.00","252.57","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "MRNA","MODERNA INC","Health Care","Equity","278,834,880.01","3.64","278,834,880.01","2,521,339.00","110.59","United States","NASDAQ","USD","1.00","USD","-" "BIIB","BIOGEN INC","Health Care","Equity","234,529,001.84","3.06","234,529,001.84","1,084,076.00","216.34","United States","NASDAQ","USD","1.00","USD","-" "MTD","METTLER TOLEDO INC","Health Care","Equity","212,370,507.36","2.77","212,370,507.36","158,979.00","1,335.84","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "ILMN","ILLUMINA INC","Health Care","Equity","164,939,196.68","2.15","164,939,196.68","1,189,351.00","138.68","United States","NASDAQ","USD","1.00","USD","-" "WAT","WATERS CORP","Health Care","Equity","153,250,207.21","2.00","153,250,207.21","443,959.00","345.19","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "ARGX","ARGENX SE ADR","Health Care","Equity","150,318,253.75","1.96","150,318,253.75","377,125.00","398.59","Belgium","NASDAQ","USD","1.00","USD","-" "ALNY","ALNYLAM PHARMACEUTICALS INC","Health Care","Equity","145,467,493.12","1.90","145,467,493.12","942,208.00","154.39","United States","NASDAQ","USD","1.00","USD","-" "BNTX","BIONTECH SE ADR","Health Care","Equity","144,577,554.03","1.89","144,577,554.03","1,555,099.00","92.97","Germany","NASDAQ","USD","1.00","USD","-" "GMAB","GENMAB SPONSORED ADR","Health Care","Equity","129,516,259.56","1.69","129,516,259.56","4,228,412.00","30.63","Denmark","NASDAQ","USD","1.00","USD","-" "BMRN","BIOMARIN PHARMACEUTICAL INC","Health Care","Equity","123,251,990.89","1.61","123,251,990.89","1,390,949.00","88.61","United States","NASDAQ","USD","1.00","USD","-" "CRL","CHARLES RIVER LABORATORIES INTERNA","Health Care","Equity","101,741,857.11","1.33","101,741,857.11","377,703.00","269.37","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "NBIX","NEUROCRINE BIOSCIENCES INC","Health Care","Equity","100,399,231.24","1.31","100,399,231.24","728,428.00","137.83","United States","NASDAQ","USD","1.00","USD","-" "INCY","INCYTE CORP","Health Care","Equity","95,271,076.32","1.24","95,271,076.32","1,667,911.00","57.12","United States","NASDAQ","USD","1.00","USD","-" "BGNE","BEIGENE ADS REPRESENTING LTD","Health Care","Equity","93,855,036.32","1.23","93,855,036.32","605,204.00","155.08","China","NASDAQ","USD","1.00","USD","-" "SRPT","SAREPTA THERAPEUTICS INC","Health Care","Equity","86,451,101.82","1.13","86,451,101.82","663,834.00","130.23","United States","NASDAQ","USD","1.00","USD","-" "TECH","BIO TECHNE CORP","Health Care","Equity","81,199,324.44","1.06","81,199,324.44","1,169,682.00","69.42","United States","NASDAQ","USD","1.00","USD","-" "UTHR","UNITED THERAPEUTICS CORP","Health Care","Equity","79,279,260.30","1.03","79,279,260.30","325,890.00","243.27","United States","NASDAQ","USD","1.00","USD","-" "NTRA","NATERA INC","Health Care","Equity","75,214,052.52","0.98","75,214,052.52","831,462.00","90.46","United States","NASDAQ","USD","1.00","USD","-" "MEDP","MEDPACE HOLDINGS INC","Health Care","Equity","74,712,623.09","0.98","74,712,623.09","185,267.00","403.27","United States","NASDAQ","USD","1.00","USD","-" "RGEN","REPLIGEN CORP","Health Care","Equity","72,197,159.25","0.94","72,197,159.25","390,783.00","184.75","United States","NASDAQ","USD","1.00","USD","-" "LEGN","LEGEND BIOTECH ADR REP CORP","Health Care","Equity","65,582,335.26","0.86","65,582,335.26","1,151,982.00","56.93","China","NASDAQ","USD","1.00","USD","-" "BRKR","BRUKER CORP","Health Care","Equity","63,524,635.72","0.83","63,524,635.72","676,802.00","93.86","United States","NASDAQ","USD","1.00","USD","-" "ASND","ASCENDIS PHARMA ADR REPRESENTING","Health Care","Equity","53,949,775.80","0.70","53,949,775.80","363,445.00","148.44","Denmark","NASDAQ","USD","1.00","USD","-" "CYTK","CYTOKINETICS INC","Health Care","Equity","53,294,996.84","0.70","53,294,996.84","746,324.00","71.41","United States","NASDAQ","USD","1.00","USD","-" "EXEL","EXELIXIS INC","Health Care","Equity","52,925,106.72","0.69","52,925,106.72","2,218,152.00","23.86","United States","NASDAQ","USD","1.00","USD","-" "PCVX","VAXCYTE INC","Health Care","Equity","52,679,651.00","0.69","52,679,651.00","769,046.00","68.50","United States","NASDAQ","USD","1.00","USD","-" "ITCI","INTRA CELLULAR THERAPIES INC","Health Care","Equity","49,398,572.16","0.64","49,398,572.16","708,528.00","69.72","United States","NASDAQ","USD","1.00","USD","-" "IONS","IONIS PHARMACEUTICALS INC","Health Care","Equity","44,913,534.82","0.59","44,913,534.82","1,005,677.00","44.66","United States","NASDAQ","USD","1.00","USD","-" "APLS","APELLIS PHARMACEUTICALS INC","Health Care","Equity","43,282,190.57","0.57","43,282,190.57","739,993.00","58.49","United States","NASDAQ","USD","1.00","USD","-" "BPMC","BLUEPRINT MEDICINES CORP","Health Care","Equity","42,810,197.28","0.56","42,810,197.28","451,632.00","94.79","United States","NASDAQ","USD","1.00","USD","-" "CRSP","CRISPR THERAPEUTICS AG","Health Care","Equity","42,063,094.96","0.55","42,063,094.96","599,531.00","70.16","United States","NASDAQ","USD","1.00","USD","-" "ROIV","ROIVANT SCIENCES LTD","Health Care","Equity","39,234,361.04","0.51","39,234,361.04","3,619,406.00","10.84","United States","NASDAQ","USD","1.00","USD","-" "HALO","HALOZYME THERAPEUTICS INC","Health Care","Equity","38,429,691.79","0.50","38,429,691.79","943,523.00","40.73","United States","NASDAQ","USD","1.00","USD","-" "ALKS","ALKERMES","Health Care","Equity","33,725,090.50","0.44","33,725,090.50","1,237,618.00","27.25","United States","NASDAQ","USD","1.00","USD","-" "RVMD","REVOLUTION MEDICINES INC","Health Care","Equity","32,495,871.20","0.42","32,495,871.20","1,024,460.00","31.72","United States","NASDAQ","USD","1.00","USD","-" "MDGL","MADRIGAL PHARMACEUTICALS INC","Health Care","Equity","31,486,048.17","0.41","31,486,048.17","121,657.00","258.81","United States","NASDAQ","USD","1.00","USD","-" "KRYS","KRYSTAL BIOTECH INC","Health Care","Equity","31,417,914.40","0.41","31,417,914.40","177,302.00","177.20","United States","NASDAQ","USD","1.00","USD","-" "BBIO","BRIDGEBIO PHARMA INC","Health Care","Equity","30,090,937.94","0.39","30,090,937.94","975,079.00","30.86","United States","NASDAQ","USD","1.00","USD","-" "INSM","INSMED INC","Health Care","Equity","29,717,821.76","0.39","29,717,821.76","1,087,768.00","27.32","United States","NASDAQ","USD","1.00","USD","-" "BHVN","BIOHAVEN LTD","Health Care","Equity","29,465,940.30","0.38","29,465,940.30","516,765.00","57.02","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "TXG","10X GENOMICS INC CLASS A","Health Care","Equity","27,260,049.95","0.36","27,260,049.95","738,955.00","36.89","United States","NASDAQ","USD","1.00","USD","-" "RARE","ULTRAGENYX PHARMACEUTICAL INC","Health Care","Equity","27,192,213.24","0.35","27,192,213.24","580,782.00","46.82","United States","NASDAQ","USD","1.00","USD","-" "FOLD","AMICUS THERAPEUTICS INC","Health Care","Equity","25,591,958.68","0.33","25,591,958.68","2,157,838.00","11.86","United States","NASDAQ","USD","1.00","USD","-" "ARWR","ARROWHEAD PHARMACEUTICALS INC","Health Care","Equity","25,201,498.70","0.33","25,201,498.70","878,101.00","28.70","United States","NASDAQ","USD","1.00","USD","-" "SWTX","SPRINGWORKS THERAPEUTICS INC","Health Care","Equity","23,667,690.90","0.31","23,667,690.90","472,409.00","50.10","United States","NASDAQ","USD","1.00","USD","-" "XENE","XENON PHARMACEUTICALS INC","Health Care","Equity","23,384,862.00","0.31","23,384,862.00","543,834.00","43.00","United States","NASDAQ","USD","1.00","USD","-" "AXSM","AXSOME THERAPEUTICS INC","Health Care","Equity","23,131,890.60","0.30","23,131,890.60","292,180.00","79.17","United States","NASDAQ","USD","1.00","USD","-" "IOVA","IOVANCE BIOTHERAPEUTICS INC","Health Care","Equity","22,810,810.80","0.30","22,810,810.80","1,617,788.00","14.10","United States","NASDAQ","USD","1.00","USD","-" "ACAD","ACADIA PHARMACEUTICALS INC","Health Care","Equity","22,431,663.80","0.29","22,431,663.80","1,232,509.00","18.20","United States","NASDAQ","USD","1.00","USD","-" "FTRE","FORTREA HOLDINGS INC","Health Care","Equity","22,060,432.80","0.29","22,060,432.80","550,410.00","40.08","United States","NASDAQ","USD","1.00","USD","-" "CRNX","CRINETICS PHARMACEUTICALS INC","Health Care","Equity","21,345,060.60","0.28","21,345,060.60","480,420.00","44.43","United States","NASDAQ","USD","1.00","USD","-" "IDYA","IDEAYA BIOSCIENCES INC","Health Care","Equity","21,257,111.03","0.28","21,257,111.03","490,813.00","43.31","United States","NASDAQ","USD","1.00","USD","-" "IMCR","IMMUNOCORE HOLDINGS ADR PLC","Health Care","Equity","19,867,160.50","0.26","19,867,160.50","312,475.00","63.58","United Kingdom","NASDAQ","USD","1.00","USD","-" "ACLX","ARCELLX INC","Health Care","Equity","19,856,614.30","0.26","19,856,614.30","281,854.00","70.45","United States","NASDAQ","USD","1.00","USD","-" "NTLA","INTELLIA THERAPEUTICS INC","Health Care","Equity","19,179,984.88","0.25","19,179,984.88","709,844.00","27.02","United States","NASDAQ","USD","1.00","USD","-" "OLK","OLINK HOLDING AB PUBL ADR","Health Care","Equity","18,738,919.20","0.24","18,738,919.20","794,022.00","23.60","Sweden","NASDAQ","USD","1.00","USD","-" "VCEL","VERICEL CORP","Health Care","Equity","18,624,037.68","0.24","18,624,037.68","355,896.00","52.33","United States","NASDAQ","USD","1.00","USD","-" "XTSLA","BLK CSH FND TREASURY SL AGENCY","Cash and/or Derivatives","Money Market","17,963,564.72","0.23","17,963,564.72","17,963,565.00","1.00","United States","-","USD","1.00","USD","-" "NUVL","NUVALENT INC CLASS A","Health Care","Equity","17,917,435.68","0.23","17,917,435.68","233,787.00","76.64","United States","NASDAQ","USD","1.00","USD","-" "MOR","MORPHOSYS ADR REPRESENTING AG","Health Care","Equity","17,560,227.46","0.23","17,560,227.46","968,039.00","18.14","Germany","NASDAQ","USD","1.00","USD","-" "DNLI","DENALI THERAPEUTICS INC","Health Care","Equity","17,488,319.23","0.23","17,488,319.23","841,999.00","20.77","United States","NASDAQ","USD","1.00","USD","-" "ARVN","ARVINAS INC","Health Care","Equity","17,453,617.67","0.23","17,453,617.67","422,299.00","41.33","United States","NASDAQ","USD","1.00","USD","-" "BEAM","BEAM THERAPEUTICS INC","Health Care","Equity","17,346,088.80","0.23","17,346,088.80","510,780.00","33.96","United States","NASDAQ","USD","1.00","USD","-" "RCKT","ROCKET PHARMACEUTICALS INC","Health Care","Equity","16,937,401.00","0.22","16,937,401.00","621,556.00","27.25","United States","NASDAQ","USD","1.00","USD","-" "RYTM","RHYTHM PHARMACEUTICALS INC","Health Care","Equity","16,366,635.60","0.21","16,366,635.60","391,640.00","41.79","United States","NASDAQ","USD","1.00","USD","-" "KYMR","KYMERA THERAPEUTICS INC","Health Care","Equity","16,178,467.50","0.21","16,178,467.50","402,750.00","40.17","United States","NASDAQ","USD","1.00","USD","-" "PTCT","PTC THERAPEUTICS INC","Health Care","Equity","16,068,322.56","0.21","16,068,322.56","545,799.00","29.44","United States","NASDAQ","USD","1.00","USD","-" "IMVT","IMMUNOVANT INC","Health Care","Equity","14,864,469.24","0.19","14,864,469.24","457,087.00","32.52","United States","NASDAQ","USD","1.00","USD","-" "MRUS","MERUS NV","Health Care","Equity","14,546,658.75","0.19","14,546,658.75","325,065.00","44.75","United States","NASDAQ","USD","1.00","USD","-" "TWST","TWIST BIOSCIENCE CORP","Health Care","Equity","14,348,507.20","0.19","14,348,507.20","416,140.00","34.48","United States","NASDAQ","USD","1.00","USD","-" "SNDX","SYNDAX PHARMACEUTICALS INC","Health Care","Equity","13,969,277.19","0.18","13,969,277.19","605,517.00","23.07","United States","NASDAQ","USD","1.00","USD","-" "MYGN","MYRIAD GENETICS INC","Health Care","Equity","13,875,396.20","0.18","13,875,396.20","648,383.00","21.40","United States","NASDAQ","USD","1.00","USD","-" "GLPG","GALAPAGOS ADR REPRESENTING NV","Health Care","Equity","13,632,798.90","0.18","13,632,798.90","413,742.00","32.95","Belgium","NASDAQ","USD","1.00","USD","-" "RNA","AVIDITY BIOSCIENCES INC","Health Care","Equity","13,153,994.66","0.17","13,153,994.66","533,198.00","24.67","United States","NASDAQ","USD","1.00","USD","-" "KROS","KEROS THERAPEUTICS INC","Health Care","Equity","13,004,095.90","0.17","13,004,095.90","201,115.00","64.66","United States","NASDAQ","USD","1.00","USD","-" "ALPN","ALPINE IMMUNE SCIENCES INC","Health Care","Equity","12,993,279.70","0.17","12,993,279.70","336,178.00","38.65","United States","NASDAQ","USD","1.00","USD","-" "VCYT","VERACYTE INC","Health Care","Equity","12,233,594.52","0.16","12,233,594.52","563,241.00","21.72","United States","NASDAQ","USD","1.00","USD","-" "DVAX","DYNAVAX TECHNOLOGIES CORP","Health Care","Equity","12,171,157.14","0.16","12,171,157.14","980,754.00","12.41","United States","NASDAQ","USD","1.00","USD","-" "AGIO","AGIOS PHARMACEUTICALS INC","Health Care","Equity","12,009,699.52","0.16","12,009,699.52","412,421.00","29.12","United States","NASDAQ","USD","1.00","USD","-" "PTGX","PROTAGONIST THERAPEUTICS INC","Health Care","Equity","11,736,437.12","0.15","11,736,437.12","412,094.00","28.48","United States","NASDAQ","USD","1.00","USD","-" "FDMT","4D MOLECULAR THERAPEUTICS INC","Health Care","Equity","11,426,711.33","0.15","11,426,711.33","318,559.00","35.87","United States","NASDAQ","USD","1.00","USD","-" "VERA","VERA THERAPEUTICS INC CLASS A","Health Care","Equity","11,414,120.94","0.15","11,414,120.94","260,418.00","43.83","United States","NASDAQ","USD","1.00","USD","-" "RXRX","RECURSION PHARMACEUTICALS INC CLAS","Health Care","Equity","11,229,174.99","0.15","11,229,174.99","1,104,147.00","10.17","United States","NASDAQ","USD","1.00","USD","-" "GERN","GERON CORP","Health Care","Equity","11,165,642.86","0.15","11,165,642.86","3,373,306.00","3.31","United States","NASDAQ","USD","1.00","USD","-" "ADMA","ADMA BIOLOGICS INC","Health Care","Equity","11,114,738.54","0.15","11,114,738.54","1,649,071.00","6.74","United States","NASDAQ","USD","1.00","USD","-" "GRFS","GRIFOLS ADR REPRESENTING ONE NON-V","Health Care","Equity","11,093,935.65","0.14","11,093,935.65","1,668,261.00","6.65","Spain","NASDAQ","USD","1.00","USD","-" "APGE","APOGEE THERAPEUTICS INC","Health Care","Equity","11,024,352.71","0.14","11,024,352.71","161,861.00","68.11","United States","NASDAQ","USD","1.00","USD","-" "DNA","GINKGO BIOWORKS HOLDINGS INC CLASS","Materials","Equity","10,960,833.40","0.14","10,960,833.40","9,964,394.00","1.10","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "NVCR","NOVOCURE LTD","Health Care","Equity","10,500,554.64","0.14","10,500,554.64","717,251.00","14.64","United States","NASDAQ","USD","1.00","USD","-" "KURA","KURA ONCOLOGY INC","Health Care","Equity","10,320,247.98","0.13","10,320,247.98","487,494.00","21.17","United States","NASDAQ","USD","1.00","USD","-" "ZLAB","ZAI LABORATORY ADR REPRESENTING LT","Health Care","Equity","10,083,682.46","0.13","10,083,682.46","622,834.00","16.19","China","NASDAQ","USD","1.00","USD","-" "GPCR","STRUCTURE THERAPEUTICS ADR INC","Health Care","Equity","10,057,159.98","0.13","10,057,159.98","234,378.00","42.91","United States","NASDAQ","USD","1.00","USD","-" "XNCR","XENCOR INC","Health Care","Equity","10,036,851.08","0.13","10,036,851.08","447,674.00","22.42","United States","NASDAQ","USD","1.00","USD","-" "MORF","MORPHIC HOLDING INC","Health Care","Equity","10,028,433.51","0.13","10,028,433.51","291,609.00","34.39","United States","NASDAQ","USD","1.00","USD","-" "IRWD","IRONWOOD PHARMA INC CLASS A","Health Care","Equity","9,895,234.18","0.13","9,895,234.18","1,147,939.00","8.62","United States","NASDAQ","USD","1.00","USD","-" "INBX","INHIBRX INC","Health Care","Equity","9,440,481.55","0.12","9,440,481.55","268,577.00","35.15","United States","NASDAQ","USD","1.00","USD","-" "MNKD","MANNKIND CORP","Health Care","Equity","9,088,958.54","0.12","9,088,958.54","1,963,058.00","4.63","United States","NASDAQ","USD","1.00","USD","-" "AKRO","AKERO THERAPEUTICS INC","Health Care","Equity","8,844,420.75","0.12","8,844,420.75","361,735.00","24.45","United States","NASDAQ","USD","1.00","USD","-" "LGND","LIGAND PHARMACEUTICALS INC","Health Care","Equity","8,816,811.70","0.12","8,816,811.70","123,710.00","71.27","United States","NASDAQ","USD","1.00","USD","-" "PRTA","PROTHENA PLC","Health Care","Equity","8,643,089.00","0.11","8,643,089.00","343,525.00","25.16","United States","NASDAQ","USD","1.00","USD","-" "STVN","STEVANATO GROUP","Health Care","Equity","8,392,868.89","0.11","8,392,868.89","263,347.00","31.87","Italy","New York Stock Exchange Inc.","USD","1.00","USD","-" "DYN","DYNE THERAPEUTICS INC","Health Care","Equity","8,241,972.00","0.11","8,241,972.00","289,192.00","28.50","United States","NASDAQ","USD","1.00","USD","-" "EWTX","EDGEWISE THERAPEUTICS INC","Health Care","Equity","8,144,895.92","0.11","8,144,895.92","453,502.00","17.96","United States","NASDAQ","USD","1.00","USD","-" "JANX","JANUX THERAPEUTICS INC","Health Care","Equity","8,058,000.00","0.11","8,058,000.00","212,500.00","37.92","United States","NASDAQ","USD","1.00","USD","-" "SANA","SANA BIOTECHNOLOGY INC","Health Care","Equity","7,930,370.00","0.10","7,930,370.00","793,037.00","10.00","United States","NASDAQ","USD","1.00","USD","-" "AUTL","AUTOLUS THERAPEUTICS ADR PLC","Health Care","Equity","7,771,514.40","0.10","7,771,514.40","1,245,435.00","6.24","United Kingdom","NASDAQ","USD","1.00","USD","-" "BCRX","BIOCRYST PHARMACEUTICALS INC","Health Care","Equity","7,652,467.40","0.10","7,652,467.40","1,485,916.00","5.15","United States","NASDAQ","USD","1.00","USD","-" "FUSN","FUSION PHARMACEUTICALS INC","Health Care","Equity","7,527,952.50","0.10","7,527,952.50","353,425.00","21.30","United States","NASDAQ","USD","1.00","USD","-" "ZNTL","ZENTALIS PHARMACEUTICALS INC","Health Care","Equity","7,261,290.89","0.09","7,261,290.89","478,031.00","15.19","United States","NASDAQ","USD","1.00","USD","-" "ETNB","89BIO INC","Health Care","Equity","7,128,274.53","0.09","7,128,274.53","630,263.00","11.31","United States","NASDAQ","USD","1.00","USD","-" "PACB","PACIFIC BIOSCIENCES OF CALIFORNIA","Health Care","Equity","7,097,287.56","0.09","7,097,287.56","1,907,873.00","3.72","United States","NASDAQ","USD","1.00","USD","-" "SAGE","SAGE THERAPEUTICS INC","Health Care","Equity","6,989,622.08","0.09","6,989,622.08","367,102.00","19.04","United States","NASDAQ","USD","1.00","USD","-" "DAWN","DAY ONE BIOPHARMACEUTICALS INC","Health Care","Equity","6,960,532.01","0.09","6,960,532.01","440,819.00","15.79","United States","NASDAQ","USD","1.00","USD","-" "ABCL","ABCELLERA BIOLOGICS INC","Health Care","Equity","6,947,875.39","0.09","6,947,875.39","1,547,411.00","4.49","Canada","NASDAQ","USD","1.00","USD","-" "MRVI","MARAVAI LIFESCIENCES HOLDINGS INC","Health Care","Equity","6,939,632.70","0.09","6,939,632.70","808,815.00","8.58","United States","NASDAQ","USD","1.00","USD","-" "MIRM","MIRUM PHARMACEUTICALS INC","Health Care","Equity","6,883,583.36","0.09","6,883,583.36","274,028.00","25.12","United States","NASDAQ","USD","1.00","USD","-" "TARS","TARSUS PHARMACEUTICALS INC","Health Care","Equity","6,687,635.64","0.09","6,687,635.64","193,452.00","34.57","United States","NASDAQ","USD","1.00","USD","-" "VIR","VIR BIOTECHNOLOGY INC","Health Care","Equity","6,639,982.40","0.09","6,639,982.40","657,424.00","10.10","United States","NASDAQ","USD","1.00","USD","-" "RGNX","REGENXBIO INC","Health Care","Equity","6,610,970.80","0.09","6,610,970.80","298,060.00","22.18","United States","NASDAQ","USD","1.00","USD","-" "MGNX","MACROGENICS INC","Health Care","Equity","6,535,709.84","0.09","6,535,709.84","436,879.00","14.96","United States","NASDAQ","USD","1.00","USD","-" "RCUS","ARCUS BIOSCIENCES INC","Health Care","Equity","6,448,343.10","0.08","6,448,343.10","354,110.00","18.21","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "SRRK","SCHOLAR ROCK HOLDING CORP","Health Care","Equity","6,271,572.15","0.08","6,271,572.15","405,927.00","15.45","United States","NASDAQ","USD","1.00","USD","-" "ARCT","ARCTURUS THERAPEUTICS HOLDINGS INC","Health Care","Equity","5,998,658.72","0.08","5,998,658.72","182,552.00","32.86","United States","NASDAQ","USD","1.00","USD","-" "QTRX","QUANTERIX CORP","Health Care","Equity","5,952,421.63","0.08","5,952,421.63","259,591.00","22.93","United States","NASDAQ","USD","1.00","USD","-" "CTKB","CYTEK BIOSCIENCES INC","Health Care","Equity","5,936,541.78","0.08","5,936,541.78","895,406.00","6.63","United States","NASDAQ","USD","1.00","USD","-" "BCYC","BICYCLE THERAPEUTICS ADR PLC","Health Care","Equity","5,792,965.30","0.08","5,792,965.30","235,966.00","24.55","United Kingdom","NASDAQ","USD","1.00","USD","-" "ARQT","ARCUTIS BIOTHERAPEUTICS INC","Health Care","Equity","5,721,902.27","0.07","5,721,902.27","596,653.00","9.59","United States","NASDAQ","USD","1.00","USD","-" "VRNA","VERONA PHARMA ADR PLC","Health Care","Equity","5,689,876.50","0.07","5,689,876.50","344,841.00","16.50","United Kingdom","NASDAQ","USD","1.00","USD","-" "IRON","DISC MEDICINE INC","Health Care","Equity","5,647,579.83","0.07","5,647,579.83","93,333.00","60.51","United States","NASDAQ","USD","1.00","USD","-" "PLRX","PLIANT THERAPEUTICS INC","Health Care","Equity","5,598,374.40","0.07","5,598,374.40","384,768.00","14.55","United States","NASDAQ","USD","1.00","USD","-" "RLAY","RELAY THERAPEUTICS INC","Health Care","Equity","5,585,275.20","0.07","5,585,275.20","684,470.00","8.16","United States","NASDAQ","USD","1.00","USD","-" "DCPH","DECIPHERA PHARMACEUTICALS INC","Health Care","Equity","5,582,915.58","0.07","5,582,915.58","367,781.00","15.18","United States","NASDAQ","USD","1.00","USD","-" "VERV","VERVE THERAPEUTICS INC","Health Care","Equity","5,427,315.68","0.07","5,427,315.68","411,472.00","13.19","United States","NASDAQ","USD","1.00","USD","-" "KNSA","KINIKSA PHARMACEUTICALS LTD CLASS","Health Care","Equity","5,158,839.29","0.07","5,158,839.29","258,071.00","19.99","United States","NASDAQ","USD","1.00","USD","-" "ZYME","ZYMEWORKS INC","Health Care","Equity","5,059,535.10","0.07","5,059,535.10","491,217.00","10.30","United States","NASDAQ","USD","1.00","USD","-" "NRIX","NURIX THERAPEUTICS INC","Health Care","Equity","4,930,688.48","0.06","4,930,688.48","339,112.00","14.54","United States","NASDAQ","USD","1.00","USD","-" "AUPH","AURINIA PHARMACEUTICALS INC","Health Care","Equity","4,724,020.00","0.06","4,724,020.00","944,804.00","5.00","United States","NASDAQ","USD","1.00","USD","-" "EDIT","EDITAS MEDICINE INC","Health Care","Equity","4,546,055.76","0.06","4,546,055.76","611,029.00","7.44","United States","NASDAQ","USD","1.00","USD","-" "TVTX","TRAVERE THERAPEUTICS INC","Health Care","Equity","4,368,203.06","0.06","4,368,203.06","569,518.00","7.67","United States","NASDAQ","USD","1.00","USD","-" "CABA","CABALETTA BIO INC","Health Care","Equity","4,358,432.40","0.06","4,358,432.40","254,136.00","17.15","United States","NASDAQ","USD","1.00","USD","-" "NUVB","NUVATION BIO INC CLASS A","Health Care","Equity","4,358,067.50","0.06","4,358,067.50","1,097,750.00","3.97","United States","New York Stock Exchange Inc.","USD","1.00","USD","-" "EXAI","EXSCIENTIA ADR PLC","Health Care","Equity","4,203,632.16","0.05","4,203,632.16","727,272.00","5.78","United Kingdom","NASDAQ","USD","1.00","USD","-" "FULC","FULCRUM THERAPEUTICS INC","Health Care","Equity","4,184,640.46","0.05","4,184,640.46","442,351.00","9.46","United States","NASDAQ","USD","1.00","USD","-" "COGT","COGENT BIOSCIENCES INC","Health Care","Equity","4,117,999.40","0.05","4,117,999.40","631,595.00","6.52","United States","NASDAQ","USD","1.00","USD","-" "YMAB","Y MABS THERAPEUTICS INC","Health Care","Equity","4,116,915.00","0.05","4,116,915.00","249,510.00","16.50","United States","NASDAQ","USD","1.00","USD","-" "CSTL","CASTLE BIOSCIENCES INC","Health Care","Equity","4,105,954.72","0.05","4,105,954.72","192,949.00","21.28","United States","NASDAQ","USD","1.00","USD","-" "NVAX","NOVAVAX INC","Health Care","Equity","4,091,430.90","0.05","4,091,430.90","843,594.00","4.85","United States","NASDAQ","USD","1.00","USD","-" "ORIC","ORIC PHARMACEUTICALS INC","Health Care","Equity","4,064,396.79","0.05","4,064,396.79","301,849.00","13.47","United States","NASDAQ","USD","1.00","USD","-" "OLMA","OLEMA PHARMACEUTICALS INC","Health Care","Equity","4,023,196.80","0.05","4,023,196.80","359,214.00","11.20","United States","NASDAQ","USD","1.00","USD","-" "CDNA","CAREDX INC","Health Care","Equity","3,930,787.48","0.05","3,930,787.48","373,649.00","10.52","United States","NASDAQ","USD","1.00","USD","-" "CNTA","CENTESSA PHARMACEUTICALS AMERICAN","Health Care","Equity","3,901,872.00","0.05","3,901,872.00","351,520.00","11.10","United Kingdom","NASDAQ","USD","1.00","USD","-" "WVE","WAVE LIFE SCIENCES LTD","Health Care","Equity","3,833,684.64","0.05","3,833,684.64","634,716.00","6.04","United States","NASDAQ","USD","1.00","USD","-" "ANAB","ANAPTYSBIO INC","Health Care","Equity","3,714,689.48","0.05","3,714,689.48","173,746.00","21.38","United States","NASDAQ","USD","1.00","USD","-" "CGEM","CULLINAN ONCOLOGY INC","Health Care","Equity","3,537,826.47","0.05","3,537,826.47","199,539.00","17.73","United States","NASDAQ","USD","1.00","USD","-" "ALLO","ALLOGENE THERAPEUTICS INC","Health Care","Equity","3,510,300.98","0.05","3,510,300.98","787,063.00","4.46","United States","NASDAQ","USD","1.00","USD","-" "MRNS","MARINUS PHARMACEUTICALS INC","Health Care","Equity","3,403,072.80","0.04","3,403,072.80","384,528.00","8.85","United States","NASDAQ","USD","1.00","USD","-" "ALEC","ALECTOR INC","Health Care","Equity","3,246,416.00","0.04","3,246,416.00","533,950.00","6.08","United States","NASDAQ","USD","1.00","USD","-" "BMEA","BIOMEA FUSION INC","Health Care","Equity","3,210,424.32","0.04","3,210,424.32","209,012.00","15.36","United States","NASDAQ","USD","1.00","USD","-" "FLGT","FULGENT GENETICS INC","Health Care","Equity","3,172,162.50","0.04","3,172,162.50","146,250.00","21.69","United States","NASDAQ","USD","1.00","USD","-" "TSHA","TAYSHA GENE THERAPIES INC","Health Care","Equity","3,129,899.50","0.04","3,129,899.50","987,350.00","3.17","United States","NASDAQ","USD","1.00","USD","-" "SPRY","ARS PHARMACEUTICALS INC","Health Care","Equity","3,117,758.88","0.04","3,117,758.88","313,028.00","9.96","United States","NASDAQ","USD","1.00","USD","-" "CMPS","COMPASS PATHWAYS ADR PLC","Health Care","Equity","3,114,214.00","0.04","3,114,214.00","327,812.00","9.50","United Kingdom","NASDAQ","USD","1.00","USD","-" "ADPT","ADAPTIVE BIOTECHNOLOGIES CORP","Health Care","Equity","3,102,704.00","0.04","3,102,704.00","1,073,600.00","2.89","United States","NASDAQ","USD","1.00","USD","-" "SLRN","ACELYRIN INC","Health Care","Equity","3,084,189.75","0.04","3,084,189.75","456,917.00","6.75","United States","NASDAQ","USD","1.00","USD","-" "TBPH","THERAVANCE BIOPHARMA INC","Health Care","Equity","3,061,706.12","0.04","3,061,706.12","339,812.00","9.01","United States","NASDAQ","USD","1.00","USD","-" "AVXL","ANAVEX LIFE SCIENCES CORP","Health Care","Equity","3,058,623.26","0.04","3,058,623.26","604,471.00","5.06","United States","NASDAQ","USD","1.00","USD","-" "ELVN","ENLIVEN THERAPEUTICS INC","Health Care","Equity","3,023,984.34","0.04","3,023,984.34","162,318.00","18.63","United States","NASDAQ","USD","1.00","USD","-" "CRBU","CARIBOU BIOSCIENCES INC","Health Care","Equity","3,021,137.92","0.04","3,021,137.92","590,066.00","5.12","United States","NASDAQ","USD","1.00","USD","-" "OPK","OPKO HEALTH INC","Health Care","Equity","2,998,454.58","0.04","2,998,454.58","2,802,294.00","1.07","United States","NASDAQ","USD","1.00","USD","-" "MXCT","MAXCYTE INC","Health Care","Equity","2,992,226.40","0.04","2,992,226.40","692,645.00","4.32","United States","NASDAQ","USD","1.00","USD","-" "RVNC","REVANCE THERAPEUTICS INC","Health Care","Equity","2,978,143.22","0.04","2,978,143.22","602,863.00","4.94","United States","NASDAQ","USD","1.00","USD","-" "TNGX","TANGO THERAPEUTICS INC","Health Care","Equity","2,928,741.20","0.04","2,928,741.20","380,356.00","7.70","United States","NASDAQ","USD","1.00","USD","-" "ITOS","ITEOS THERAPEUTICS INC","Health Care","Equity","2,874,747.60","0.04","2,874,747.60","218,280.00","13.17","United States","NASDAQ","USD","1.00","USD","-" "URGN","UROGEN PHARMA LTD","Health Care","Equity","2,818,823.04","0.04","2,818,823.04","188,424.00","14.96","United States","NASDAQ","USD","1.00","USD","-" "REPL","REPLIMUNE GROUP INC","Health Care","Equity","2,735,609.25","0.04","2,735,609.25","331,589.00","8.25","United States","NASDAQ","USD","1.00","USD","-" "TRML","TOURMALINE BIO INC","Health Care","Equity","2,664,071.50","0.03","2,664,071.50","116,335.00","22.90","United States","NASDAQ","USD","1.00","USD","-" "VYGR","VOYAGER THERAPEUTICS INC","Health Care","Equity","2,583,915.04","0.03","2,583,915.04","270,284.00","9.56","United States","NASDAQ","USD","1.00","USD","-" "ABUS","ARBUTUS BIOPHARMA CORP","Health Care","Equity","2,487,721.60","0.03","2,487,721.60","956,816.00","2.60","United States","NASDAQ","USD","1.00","USD","-" "SVRA","SAVARA INC","Health Care","Equity","2,425,843.90","0.03","2,425,843.90","500,174.00","4.85","United States","NASDAQ","USD","1.00","USD","-" "ALXO","ALX ONCOLOGY HOLDINGS INC","Health Care","Equity","2,361,128.35","0.03","2,361,128.35","206,935.00","11.41","United States","NASDAQ","USD","1.00","USD","-" "SMMT","SUMMIT THERAPEUTICS INC","Health Care","Equity","2,360,002.50","0.03","2,360,002.50","629,334.00","3.75","United States","NASDAQ","USD","1.00","USD","-" "MGTX","MEIRAGTX HOLDINGS PLC","Health Care","Equity","2,330,097.57","0.03","2,330,097.57","375,217.00","6.21","United States","NASDAQ","USD","1.00","USD","-" "AVIR","ATEA PHARMACEUTICALS INC","Health Care","Equity","2,256,280.00","0.03","2,256,280.00","564,070.00","4.00","United States","NASDAQ","USD","1.00","USD","-" "PHAT","PHATHOM PHARMACEUTICALS INC","Health Care","Equity","2,185,435.85","0.03","2,185,435.85","197,777.00","11.05","United States","NASDAQ","USD","1.00","USD","-" "CVAC","CUREVAC NV","Health Care","Equity","2,069,281.65","0.03","2,069,281.65","678,453.00","3.05","Germany","NASDAQ","USD","1.00","USD","-" "VTYX","VENTYX BIOSCIENCES INC","Health Care","Equity","2,069,157.42","0.03","2,069,157.42","356,444.00","5.80","United States","NASDAQ","USD","1.00","USD","-" "KALV","KALVISTA PHARMACEUTICALS INC","Health Care","Equity","2,054,890.89","0.03","2,054,890.89","185,627.00","11.07","United States","NASDAQ","USD","1.00","USD","-" "RAPT","RAPT THERAPEUTICS INC","Health Care","Equity","2,052,069.35","0.03","2,052,069.35","229,795.00","8.93","United States","NASDAQ","USD","1.00","USD","-" "CHRS","COHERUS BIOSCIENCES INC","Health Care","Equity","1,977,633.68","0.03","1,977,633.68","817,204.00","2.42","United States","NASDAQ","USD","1.00","USD","-" "BLUE","BLUEBIRD BIO INC","Health Care","Equity","1,951,405.36","0.03","1,951,405.36","1,429,601.00","1.37","United States","NASDAQ","USD","1.00","USD","-" "PRME","PRIME MEDICINE INC","Health Care","Equity","1,892,015.84","0.02","1,892,015.84","279,884.00","6.76","United States","NASDAQ","USD","1.00","USD","-" "LYEL","LYELL IMMUNOPHARMA INC","Health Care","Equity","1,834,221.12","0.02","1,834,221.12","899,128.00","2.04","United States","NASDAQ","USD","1.00","USD","-" "SGAFT","CASH COLLATERAL USD SGAFT","Cash and/or Derivatives","Cash Collateral and Margins","1,834,000.00","0.02","1,834,000.00","1,834,000.00","100.00","United States","-","USD","1.00","USD","Sep 01, 2016" "TERN","TERNS PHARMACEUTICALS INC","Health Care","Equity","1,805,298.88","0.02","1,805,298.88","293,068.00","6.16","United States","NASDAQ","USD","1.00","USD","-" "IMMP","IMMUTEP ADS REPRESENTING LTD","Health Care","Equity","1,791,209.40","0.02","1,791,209.40","749,460.00","2.39","Australia","NASDAQ","USD","1.00","USD","-" "HUMA","HUMACYTE INC","Health Care","Equity","1,785,203.20","0.02","1,785,203.20","575,872.00","3.10","United States","NASDAQ","USD","1.00","USD","-" "QURE","UNIQURE NV","Health Care","Equity","1,760,116.45","0.02","1,760,116.45","325,345.00","5.41","United States","NASDAQ","USD","1.00","USD","-" "NBTX","NANOBIOTIX ADR REPRESENTING SA","Health Care","Equity","1,609,432.90","0.02","1,609,432.90","253,454.00","6.35","France","NASDAQ","USD","1.00","USD","-" "ATAI","ATAI LIFE SCIENCES N V NV","Health Care","Equity","1,575,731.63","0.02","1,575,731.63","880,297.00","1.79","United States","NASDAQ","USD","1.00","USD","-" "VNDA","VANDA PHARMACEUTICALS INC","Health Care","Equity","1,566,985.36","0.02","1,566,985.36","402,824.00","3.89","United States","NASDAQ","USD","1.00","USD","-" "MLYS","MINERALYS THERAPEUTICS INC","Health Care","Equity","1,385,620.38","0.02","1,385,620.38","108,421.00","12.78","United States","NASDAQ","USD","1.00","USD","-" "OVID","OVID THERAPEUTICS INC","Health Care","Equity","1,369,816.00","0.02","1,369,816.00","449,120.00","3.05","United States","NASDAQ","USD","1.00","USD","-" "ERAS","ERASCA INC","Health Care","Equity","1,366,113.72","0.02","1,366,113.72","663,162.00","2.06","United States","NASDAQ","USD","1.00","USD","-" "PGEN","PRECIGEN INC","Health Care","Equity","1,342,872.55","0.02","1,342,872.55","926,119.00","1.45","United States","NASDAQ","USD","1.00","USD","-" "ACIU","AC IMMUNE SA","Health Care","Equity","1,301,160.78","0.02","1,301,160.78","429,426.00","3.03","Switzerland","NASDAQ","USD","1.00","USD","-" "AMLX","AMYLYX PHARMACEUTICALS INC","Health Care","Equity","1,170,728.64","0.02","1,170,728.64","406,503.00","2.88","United States","NASDAQ","USD","1.00","USD","-" "THRD","THIRD HARMONIC BIO INC","Health Care","Equity","1,142,157.76","0.01","1,142,157.76","120,608.00","9.47","United States","NASDAQ","USD","1.00","USD","-" "NAUT","NAUTILUS BIOTECHNOLGY INC","Health Care","Equity","1,134,151.57","0.01","1,134,151.57","409,441.00","2.77","United States","NASDAQ","USD","1.00","USD","-" "ACRS","ACLARIS THERAPEUTICS INC","Health Care","Equity","674,587.62","0.01","674,587.62","535,387.00","1.26","United States","NASDAQ","USD","1.00","USD","-" "RPHM","RENEO PHARMACEUTICALS INC","Health Care","Equity","326,274.30","0.00","326,274.30","197,742.00","1.65","United States","NASDAQ","USD","1.00","USD","-" "ADRO","CHINOOK THERAPEUTICS INC","Health Care","Equity","141,223.28","0.00","141,223.28","320,962.00","0.44","United States","NO MARKET (E.G. UNLISTED)","USD","1.00","USD","-" "-","AKOUOS CVRS Prvt","Consumer Staples","Equity","124,098.73","0.00","124,098.73","157,087.00","0.79","United States","NO MARKET (E.G. UNLISTED)","USD","1.00","USD","-" "-","ALEXION PHARMACEUTICALS CVR","Health Care","Equity","1,891.52","0.00","1,891.52","4,112.00","0.46","United States","-","USD","1.00","USD","-" "-","CARTESIAN THERAPEUTICS INC","Health Care","Equity","609.80","0.00","609.80","6,098.00","0.10","United States","NASDAQ","USD","1.00","USD","-" "IXCM4","E-MINI HEALTH CARE SECTOR JUN 24","Cash and/or Derivatives","Futures","0.00","0.00","6,187,720.00","41.00","1,509.20","-","Chicago Mercantile Exchange","USD","1.00","USD","-" "-","OMNIAB INC $12.50 VESTING Prvt","Health Care","Equity","0.47","0.00","0.47","46,839.00","0.00","United States","NO MARKET (E.G. UNLISTED)","USD","1.00","USD","-" "-","OMNIAB INC $15.00 VESTING Prvt","Health Care","Equity","0.47","0.00","0.47","46,839.00","0.00","United States","NO MARKET (E.G. UNLISTED)","USD","1.00","USD","-" "RTYM4","RUSSELL 2000 EMINI CME JUN 24","Cash and/or Derivatives","Futures","0.00","0.00","3,100,680.00","29.00","2,138.40","-","Chicago Mercantile Exchange","USD","1.00","USD","-" "USD","USD CASH","Cash and/or Derivatives","Cash","-9,639,553.04","-0.13","-9,639,553.04","-9,639,553.00","100.00","United States","-","USD","1.00","USD","-"   "The content contained herein is owned or licensed by BlackRock and/or its third-party information providers and is protected by applicable copyrights, trademarks, service marks, and/or other intellectual property rights. Such content is solely for your personal, non-commercial use. Accordingly, you may not copy, distribute, modify, post, frame or deep link this content. You may download material displayed on this Website for your personal use provided you also retain all copyright and other proprietary notices contained on the materials. Modification or use of the materials for any other purpose violates BlackRock's intellectual property rights. Holdings subject to change. See www.iShares.com for the most recent funds holdings. The values for “price” shown herein generally represent a price provided by a third-party pricing vendor for the portfolio holding and do not reflect the impact of systematic fair valuation (“the vendor price”). The vendor price is not necessarily the price at which the Fund values the portfolio holding for the purposes of determining its net asset value (the “valuation price”). Additionally, where applicable, foreign currency exchange rates with respect to the portfolio holdings denominated in non-U.S. currencies for the valuation price will be generally determined as of the close of business on the New York Stock Exchange, whereas for the vendor price will be generally determined as of 4 p.m. London. The values shown herein for “market value,” “weight,” and “notional value” (the “calculated values”) are based off of the vendor price and may have been different if the valuation price were to have been used to calculate such values. The vendor price is as of the most recent practicable date and may not necessarily be as of the date shown above. Please see the “Determination of Net Asset Value” section of each Fund’s prospectus for additional information on the Fund’s valuation policies and procedures. CAREFULLY CONSIDER THE FUNDS' INVESTMENT OBJECTIVES, RISK FACTORS, AND CHARGES AND EXPENSES BEFORE INVESTING. THIS AND OTHER INFORMATION CAN BE FOUND IN THE FUNDS' PROSPECTUSES OR, IF AVAILABLE, THE SUMMARY PROSPECTUSES WHICH MAY BE OBTAINED BY VISITING WWW.ISHARES.COM OR WWW.BLACKROCK.COM. READ THE PROSPECTUS CAREFULLY BEFORE INVESTING. INVESTING INVOLVES RISK, INCLUDING POSSIBLE LOSS OF PRINCIPAL. This information should not be relied upon as research, investment advice, or a recommendation regarding any products, strategies, or any security in particular. This material is strictly for illustrative, educational, or informational purposes and is subject to change. The Funds are distributed by BlackRock Investments, LLC (together with its affiliates, “BlackRock”). The iShares Funds are not sponsored, endorsed, issued, sold or promoted by Bloomberg, BlackRock Index Services, LLC, Cboe Global Indices, LLC, Cohen & Steers, European Public Real Estate Association (“EPRA® ”), FTSE International Limited (“FTSE”), ICE Data Indices, LLC, NSE Indices Ltd, JPMorgan, JPX Group, London Stock Exchange Group (“LSEG”), MSCI Inc., Markit Indices Limited, Morningstar, Inc., Nasdaq, Inc., National Association of Real Estate Investment Trusts (“NAREIT”), Nikkei, Inc., Russell, S&P Dow Jones Indices LLC or STOXX Ltd. None of these companies make any representation regarding the advisability of investing in the Funds. With the exception of BlackRock Index Services, LLC, who is an affiliate, BlackRock Investments, LLC is not affiliated with the companies listed above. Neither FTSE, LSEG, nor NAREIT makes any warranty regarding the FTSE Nareit Equity REITS Index, FTSE Nareit All Residential Capped Index or FTSE Nareit All Mortgage Capped Index. Neither FTSE, EPRA, LSEG, nor NAREIT makes any warranty regarding the FTSE EPRA Nareit Developed ex-U.S. Index, FTSE EPRA Nareit Developed Green Target Index or FTSE EPRA Nareit Global REITs Index. “FTSE®” is a trademark of London Stock Exchange Group companies and is used by FTSE under license. ©2023 BlackRock, Inc or its affiliates. All rights reserved. iSHARES, iBONDS and BLACKROCK are trademarks of BlackRock, Inc. or its affiliates. All other trademarks are those of their respective owners. iCRMH0323U/S-2742939"

Exposure Breakdowns

Exposure Breakdowns

as of Mar 27, 2024

% of Market Value

Type Fund
Allocations are subject to change.

Literature

Literature

 

How to Buy iShares ETFs

How to Buy iShares ETFs

There are many ways to access iShares ETFs. Learn how you can add them to your portfolio.